Vicenin-1
Based on 1 Customer Validation
Vicenin 1 is a C-glycosylflavone that has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM).
For research use only. We do not sell to patients.
- Purity : 98.60%
- CAS No.: 35927-38-9
- Formula: C26H28O14
- Molecular Weight:564.49
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
IC50: 52.50 μM (ACE)[1]
In Vitro
The target-isolated C-glycosylflavone (Vicenin 1) is evaluated for inhibitory activities. Vicenin 1 embodies effective ACE inhibitory activities with an IC50 value of 52.50 μM. The tested compound 3 (Vicenin 1) shows activity via the generation of chelate complexes within the active center of ACE[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 35927-38-9
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Appearance Solid
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Molecular Weight 564.49
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Formula C26H28O14
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Color Off-white to yellow
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SMILES
OC1=C([C@H]2[C@@H]([C@H]([C@H](O)CO2)O)O)C(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C1[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (177.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7715 mL | 8.8576 mL | 17.7151 mL | 44.2878 mL |
| 5 mM | 0.3543 mL | 1.7715 mL | 3.5430 mL | 8.8576 mL | |
| 10 mM | 0.1772 mL | 0.8858 mL | 1.7715 mL | 4.4288 mL | |
| 15 mM | 0.1181 mL | 0.5905 mL | 1.1810 mL | 2.9525 mL | |
| 20 mM | 0.0886 mL | 0.4429 mL | 0.8858 mL | 2.2144 mL | |
| 25 mM | 0.0709 mL | 0.3543 mL | 0.7086 mL | 1.7715 mL | |
| 30 mM | 0.0591 mL | 0.2953 mL | 0.5905 mL | 1.4763 mL | |
| 40 mM | 0.0443 mL | 0.2214 mL | 0.4429 mL | 1.1072 mL | |
| 50 mM | 0.0354 mL | 0.1772 mL | 0.3543 mL | 0.8858 mL | |
| 60 mM | 0.0295 mL | 0.1476 mL | 0.2953 mL | 0.7381 mL | |
| 80 mM | 0.0221 mL | 0.1107 mL | 0.2214 mL | 0.5536 mL | |
| 100 mM | 0.0177 mL | 0.0886 mL | 0.1772 mL | 0.4429 mL |
Vicenin-1 Related Classifications
HY-125112 Related Classifications
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