VMPWDEWLTKRKPELP
VMPWDEWLTKRKPELP is a chikungunya virus (CHIKV) nsP2 protease inhibitor with a IC50 of 4.6 μM and a Kd of 1.39 μM. VMPWDEWLTKRKPELP can be used for the research of chikungunya fever.
For research use only. We do not sell to patients.
- Formula: C95H145N23O24S
- Molecular Weight:2025.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
VMPWDEWLTKRKPELP (P1) (0-100 μM; overnight, 4 h, overnight) shows low cytotoxicity to cultured cells at concentrations up to 100 μM, providing a safe margin relative to its IC50 of 4.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:unspecified cultured cells
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Concentration:0-100 μM
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Incubation Time:overnight (peptide treatment); 4 h (MTT incubation); overnight (solubilization incubation)
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Result:Exhibited low cytotoxicity, with no significant toxicity observed at concentrations up to 100 μM, which is approximately 20 times higher than its IC50 value.
Chemical Information
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Molecular Weight 2025.37
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Formula C95H145N23O24S
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Sequence
Val-Met-Pro-Trp-Asp-Glu-Trp-Leu-Thr-Lys-Arg-Lys-Pro-Glu-Leu-Pro
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Sequence Shortening
VMPWDEWLTKRKPELP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)