VU6080824 hydrochloride
Based on 1 Customer Validation
VU6080824 (hydrochloride), a derivative of ML-133 (HY-100230), is an inward-rectifier potassium channel (Kir2.1) inhibitor with an IC50 of 0.35 μM. VU6080824 (hydrochloride) has superior thallium flux and manual patch clamp (MPC) functional potency.
For research use only. We do not sell to patients.
- Purity: 98.88%
- Formula: C22H24ClNO2
- Molecular Weight:369.88
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 369.88
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Formula C22H24ClNO2
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Color White to off-white
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SMILES
COC1=CC=C(C=C1)CNCC2=CC=C(C3=CC=CC(OC)=C3)C=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 20 mg/mL (54.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7036 mL | 13.5179 mL | 27.0358 mL | 67.5895 mL |
| 5 mM | 0.5407 mL | 2.7036 mL | 5.4072 mL | 13.5179 mL | |
| 10 mM | 0.2704 mL | 1.3518 mL | 2.7036 mL | 6.7589 mL | |
| 15 mM | 0.1802 mL | 0.9012 mL | 1.8024 mL | 4.5060 mL | |
| 20 mM | 0.1352 mL | 0.6759 mL | 1.3518 mL | 3.3795 mL | |
| 25 mM | 0.1081 mL | 0.5407 mL | 1.0814 mL | 2.7036 mL | |
| 30 mM | 0.0901 mL | 0.4506 mL | 0.9012 mL | 2.2530 mL | |
| 40 mM | 0.0676 mL | 0.3379 mL | 0.6759 mL | 1.6897 mL | |
| 50 mM | 0.0541 mL | 0.2704 mL | 0.5407 mL | 1.3518 mL |
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