WAY 629 hydrochloride
Based on 1 Customer Validation
WAY 629 hydrochloride is a potent and selective 5-HT2C agonist with EC50s of 426, 260000 nM for 5-HT2C and 5-HT2A, respectively. WAY 629 hydrochloride decreases feeding behavior.
For research use only. We do not sell to patients.
- Purity: 95.56%
- CAS No.: 57756-44-2
- Formula: C15H19ClN2
- Molecular Weight:262.78
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All 5-HT Receptor Isoforms
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Biological Activity
|
5-HT2A Receptor |
5-HT2C Receptor |
5-HT2C Receptor 426 nM (EC50) |
5-HT2A Receptor 260000 nM (EC50) |
WAY 629 hydrochloride (21 mg/kg; i.p.) decreases the expression of NPY mRNA in mice brains[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:WT mice[2]
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Dosage:21 mg/kg
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Administration:I.p.
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Result:Decreased the expression of NPY mRNA.
Chemical Information
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CAS No. 57756-44-2
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Appearance Solid
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Molecular Weight 262.78
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Formula C15H19ClN2
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Color Light yellow to yellow
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SMILES
[H]Cl.N1(CCNC2)C3=C(C4=CC=CC2=C41)CCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 12.5 mg/mL (47.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Sabb AL, et al. Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor. Bioorg Med Chem Lett. 2004 May 17;14(10):2603-7. [Content Brief]
[2]. Aoki M, et al. Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. Eur J Neurosci. 2016 May;43(9):1219-28. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8055 mL | 19.0273 mL | 38.0546 mL | 95.1366 mL |
| 5 mM | 0.7611 mL | 3.8055 mL | 7.6109 mL | 19.0273 mL | |
| 10 mM | 0.3805 mL | 1.9027 mL | 3.8055 mL | 9.5137 mL | |
| 15 mM | 0.2537 mL | 1.2685 mL | 2.5370 mL | 6.3424 mL | |
| 20 mM | 0.1903 mL | 0.9514 mL | 1.9027 mL | 4.7568 mL | |
| 25 mM | 0.1522 mL | 0.7611 mL | 1.5222 mL | 3.8055 mL | |
| 30 mM | 0.1268 mL | 0.6342 mL | 1.2685 mL | 3.1712 mL | |
| 40 mM | 0.0951 mL | 0.4757 mL | 0.9514 mL | 2.3784 mL |
WAY 629 hydrochloride Related Classifications
HY-103144 Related Classifications
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