YIGSRC 

YIGSRC is a laminin-mimetic peptide. YIGSRC supports endothelial cell adhesion and tube formation. YIGSRC contains a cysteine residue for chemical modification to hydrogels via thiol-ene reaction. YIGSRC can be chemically modified onto hydrogels to improve in vitro vascularization^[1].

YIGSRC peptide (1.25 mM; 24 h) enhances spreading and tubular structure formation of human umbilical vein endothelial cells in non-porous hydrogels, increasing the HUVEC area relative to unmodified hydrogels^[1].
YIGSRC peptide (1.25 mM; 24 h) causes a minor, statistically significant increase in the area of human umbilical vein endothelial cells in microfiber network hydrogels, though the hydrogel's porous microstructure has a more dominant effect on cellular spreading^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

697.80

C₂₉H₄₇N₉O₉S

123946-91-8

Tyr-Ile-Gly-Ser-Arg-Cys

YIGSRC

O=C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)[C@H](CC1=CC=C(C=C1)O)N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Nishiguchi A, et al. Development of Phase-Separating Microfiber Network Hydrogels to Promote In Vitro Vascularization. Biomacromolecules. 2024;25(9):6146-6154.