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Cat. No.: HY-179610

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YU185530

YU185530 is a JARID1 histone demethylase inhibitor.

For research use only. We do not sell to patients.

CAS No.: 951971-87-2
Formula: C₁₉H₂₀N₂O₄
Molecular Weight:340.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

YU185530 Chemical Structure

CAS No.: 951971-87-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

YU185530 is a JARID1 histone demethylase inhibitor^[1].

All Histone Demethylase Isoforms :

In Vitro

YU185530 exhibits inhibitory activity against JARID1 histone demethylase in cell-free biochemical assays, with a measured activity value of 46.52^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 951971-87-2
Molecular Weight 340.37
Formula C₁₉H₂₀N₂O₄
SMILES

O=C1C2=C(CC(C)(C1)C)NC3=C(C2C4=CC=C(C(O)=C4)O)C(C)=NO3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Qin Yan, et al. Identification of small molecule inhibitors of jumonji at-rich interactive domain 1a (jarid1a) and 1b (jarid1b) histone demethylase. WO2014055634A1. WIPO (PCT). 2013-10-02.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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YU185530

All Histone Demethylase Isoforms