1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. ZP 120C

ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

ZP 120C Chemical Structure

ZP 120C Chemical Structure

CAS No. : 383123-18-0

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Description

ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].

IC50 & Target[1]

NOP Receptor/ORL1

 

In Vitro

ZP 120C (1 nM) inhibits electrically induced contraction of the mouse vas deferen[2].
ZP 120C (1 μM) inhibits electrical field stimulation (EFS)-induced contractions in rat arteries[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

ZP 120C (1 nM/kg/min, i.v., 2.5 h) displays an aquaretic effect in conscious, chronically instrumented rats with congestive heart failure (CHF)[1]
. ZP 120C (1 nM, i.c.v., 30 min) produces pronociceptive effects in the tail withdrawal assay and decreases locomotor activity in mice[2]
.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats induced by left coronary artery ligation (LCAL)[1]
Dosage: 1 nM/kg/min
Administration: Intravenous injection (i.v.), 2.5 h of constant intravenous infusion
Result: Increased diuresis, free water clearance, fractional water excretion, and fractional distal water excretion.
Clinical Trial
Molecular Weight

1781.20

Formula

C85HN27O15

CAS No.
Sequence Shortening

Ac-RYYRWKKKKKKK-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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ZP 120C Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ZP 120C
Cat. No.:
HY-106234
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