1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. α-Glucosidase-IN-30

α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki  of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study.

For research use only. We do not sell to patients.

α-Glucosidase-IN-30 Chemical Structure

α-Glucosidase-IN-30 Chemical Structure

CAS No. : 2966859-35-6

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Description

α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki  of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study[1].

IC50 & Target

49.0 µM (α-glucosidase)

In Vitro

α-Glucosidase-IN-30 (compound 8c) shows no cytotoxic activity against the cancer and normal cell lines MCF-7 and HDF (IC50 > 200 μM), respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

389.41

Formula

C20H19N7O2

CAS No.
SMILES

O=C(NCC1=CN(CC(NC2=CC(C)=CC=C2)=O)N=N1)C3=NC4=CC=CC=C4N3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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α-Glucosidase-IN-30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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α-Glucosidase-IN-30
Cat. No.:
HY-155105
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