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Cat. No.: HY-178742

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α-Glucosidase-IN-99

α-Glucosidase-IN-99 (Compound 21) is an α-Glucosidase inhibitor, with an IC₅₀ of 52.79 μM. α-Glucosidase-IN-99 can be used for the study of type 2 diabetes.

For research use only. We do not sell to patients.

Formula: C₂₀H₂₀F₃N₃O
Molecular Weight:375.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

α-Glucosidase-IN-99 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

α-Glucosidase-IN-99 (Compound 21) is an α-Glucosidase inhibitor, with an IC₅₀ of 52.79 μM. α-Glucosidase-IN-99 can be used for the study of type 2 diabetes^[1].

Chemical Information

Molecular Weight 375.39
Formula C₂₀H₂₀F₃N₃O
SMILES

FC(F)(OC1=CC=CC=C1C2CC(C3=CC=C(C=C3)N4CCCC4)=NN2)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kurşun Aktar BS, et al. Novel Pyrrolidine-Based Pyrazolines as α‑Glucosidase Inhibitors: Microwave-Assisted Synthesis, Antidiabetic Activity, In Silico ADMET Prediction, Molecular Docking, and Molecular Dynamics Simulations. ACS Omega. 2025 Sep 22;10(39):45450-45464. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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