1,6-Dichlorohexane
Based on 1 Customer Validation
1,6-Dichlorohexane is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 2163-00-0
- Formula: C6H12Cl2
- Molecular Weight:155.06
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E86 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2163-00-0
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Appearance Liquid
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Molecular Weight 155.06
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Formula C6H12Cl2
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Color Colorless to light yellow
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SMILES
ClCCCCCCCl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (644.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (239 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4491 mL | 32.2456 mL | 64.4912 mL | 161.2279 mL |
| 5 mM | 1.2898 mL | 6.4491 mL | 12.8982 mL | 32.2456 mL | |
| 10 mM | 0.6449 mL | 3.2246 mL | 6.4491 mL | 16.1228 mL | |
| 15 mM | 0.4299 mL | 2.1497 mL | 4.2994 mL | 10.7485 mL | |
| 20 mM | 0.3225 mL | 1.6123 mL | 3.2246 mL | 8.0614 mL | |
| 25 mM | 0.2580 mL | 1.2898 mL | 2.5796 mL | 6.4491 mL | |
| 30 mM | 0.2150 mL | 1.0749 mL | 2.1497 mL | 5.3743 mL | |
| 40 mM | 0.1612 mL | 0.8061 mL | 1.6123 mL | 4.0307 mL | |
| 50 mM | 0.1290 mL | 0.6449 mL | 1.2898 mL | 3.2246 mL | |
| 60 mM | 0.1075 mL | 0.5374 mL | 1.0749 mL | 2.6871 mL | |
| 80 mM | 0.0806 mL | 0.4031 mL | 0.8061 mL | 2.0153 mL | |
| 100 mM | 0.0645 mL | 0.3225 mL | 0.6449 mL | 1.6123 mL |
1,6-Dichlorohexane Related Classifications
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