1,7-Dibromoheptane
Based on 1 Customer Validation
1,7-Dibromoheptane is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.64%
- CAS No.: 4549-31-9
- Formula: C7H14Br2
- Molecular Weight:258.00
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E89 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4549-31-9
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Appearance Liquid
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Molecular Weight 258.00
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Formula C7H14Br2
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Color Colorless to light yellow
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SMILES
BrCCCCCCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (387.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (239 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8760 mL | 19.3798 mL | 38.7597 mL | 96.8992 mL |
| 5 mM | 0.7752 mL | 3.8760 mL | 7.7519 mL | 19.3798 mL | |
| 10 mM | 0.3876 mL | 1.9380 mL | 3.8760 mL | 9.6899 mL | |
| 15 mM | 0.2584 mL | 1.2920 mL | 2.5840 mL | 6.4599 mL | |
| 20 mM | 0.1938 mL | 0.9690 mL | 1.9380 mL | 4.8450 mL | |
| 25 mM | 0.1550 mL | 0.7752 mL | 1.5504 mL | 3.8760 mL | |
| 30 mM | 0.1292 mL | 0.6460 mL | 1.2920 mL | 3.2300 mL | |
| 40 mM | 0.0969 mL | 0.4845 mL | 0.9690 mL | 2.4225 mL | |
| 50 mM | 0.0775 mL | 0.3876 mL | 0.7752 mL | 1.9380 mL | |
| 60 mM | 0.0646 mL | 0.3230 mL | 0.6460 mL | 1.6150 mL | |
| 80 mM | 0.0484 mL | 0.2422 mL | 0.4845 mL | 1.2112 mL | |
| 100 mM | 0.0388 mL | 0.1938 mL | 0.3876 mL | 0.9690 mL |
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