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Cat. No.: HY-187154

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1-Decanesulfonic acid

1-Decanesulfonic acid is an alkanesulfonate anionic surfactant that acts as a neutralizer of plasminogen activator inhibitor-1 (PAI-1). 1-Decanesulfonic acid binds to the hydrophobic region in the flexible linker domain of active PAI-1. 1-Decanesulfonic acid induces PAI-1 polymerization via a two-step neutralization mechanism.

For research use only. We do not sell to patients.

CAS No.: 20283-21-0
Formula: C₁₀H₂₂O₃S
Molecular Weight:222.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

1-Decanesulfonic acid Chemical Structure

CAS No.: 20283-21-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

1-Decanesulfonic acid can be separated, quantified, and preconcentrated in water and seawater samples via ion chromatography with suppressed conductivity detection, with a detection limit of 0.14 μM and quantitative recovery (101%) from spiked seawater^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 20283-21-0
Molecular Weight 222.34
Formula C₁₀H₂₂O₃S
SMILES

O=S(=O)(O)CCCCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Egelund R, et al. A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization. J Biol Chem. 2001 Apr 20;276(16):13077-86. [Content Brief]

[2]. Bruzzoniti MC, et al. Determination of sulfonic acids and alkylsulfates by ion chromatography in water. Talanta. 2008 May 15;75(3):734-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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