1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Methylguanidine hydrochloride

1-Methylguanidine hydrochloride 

Cat. No.: HY-W005028 Purity: ≥98.0%
COA Handling Instructions

1-Methylguanidine hydrochloride is an endogenous metabolite.

For research use only. We do not sell to patients.

1-Methylguanidine hydrochloride Chemical Structure

1-Methylguanidine hydrochloride Chemical Structure

CAS No. : 21770-81-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
500 mg USD 50 In-stock
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

1-Methylguanidine hydrochloride is an endogenous metabolite.

Molecular Weight

109.56

Formula

C2H8ClN3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC(NC)=N.[H]Cl

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (2281.85 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.1274 mL 45.6371 mL 91.2742 mL
5 mM 1.8255 mL 9.1274 mL 18.2548 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (912.74 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 9.1274 mL 45.6371 mL 91.2742 mL 228.1855 mL
5 mM 1.8255 mL 9.1274 mL 18.2548 mL 45.6371 mL
10 mM 0.9127 mL 4.5637 mL 9.1274 mL 22.8185 mL
15 mM 0.6085 mL 3.0425 mL 6.0849 mL 15.2124 mL
20 mM 0.4564 mL 2.2819 mL 4.5637 mL 11.4093 mL
25 mM 0.3651 mL 1.8255 mL 3.6510 mL 9.1274 mL
30 mM 0.3042 mL 1.5212 mL 3.0425 mL 7.6062 mL
40 mM 0.2282 mL 1.1409 mL 2.2819 mL 5.7046 mL
50 mM 0.1825 mL 0.9127 mL 1.8255 mL 4.5637 mL
60 mM 0.1521 mL 0.7606 mL 1.5212 mL 3.8031 mL
80 mM 0.1141 mL 0.5705 mL 1.1409 mL 2.8523 mL
100 mM 0.0913 mL 0.4564 mL 0.9127 mL 2.2819 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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1-Methylguanidine hydrochloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1-Methylguanidine hydrochloride
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