2-Ethylbenzimidazole
Based on 1 Customer Validation
2-Ethylbenzimidazole is an anti-fungal agent. 2-Ethylbenzimidazole inhibits the growth of unicellular fungi and filamentous fungi. 2-Ethylbenzimidazole is applicable for the research of fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 1848-84-6
- Formula: C9H10N2
- Molecular Weight:146.19
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BHK-21 | EC50 |
>100 μM
Compound: 75
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Antiviral activity against Reovirus type-1 infected in BHK21 cells assessed as inhibition of virus-induced cytopathogenicity after 3 to 4 days by MTT assay
Antiviral activity against Reovirus type-1 infected in BHK21 cells assessed as inhibition of virus-induced cytopathogenicity after 3 to 4 days by MTT assay
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[PMID: 25082514] |
| MT4 | CC50 |
>100 μM
Compound: 75
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Cytotoxicity against mock-infected human MT4 cells after 96 hrs by MTT assay
Cytotoxicity against mock-infected human MT4 cells after 96 hrs by MTT assay
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[PMID: 25082514] |
| MT4 | EC50 |
>100 μM
Compound: 75
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Antiviral activity against HIV1 infected in human MT4 cells assessed as inhibition of virus-induced cytopathogenicity after 4 days by MTT assay
Antiviral activity against HIV1 infected in human MT4 cells assessed as inhibition of virus-induced cytopathogenicity after 4 days by MTT assay
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[PMID: 25082514] |
| Vero | EC50 |
>100 μM
Compound: 75
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Antiviral activity against Coxsackievirus B5 infected in african green monkey Vero 76 cells assessed as reduction in plaque number after 3 days by plaque reduction assay
Antiviral activity against Coxsackievirus B5 infected in african green monkey Vero 76 cells assessed as reduction in plaque number after 3 days by plaque reduction assay
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[PMID: 25082514] |
| Vero 76 | CC50 |
>100 μM
Compound: 75
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Cytotoxicity against mock-infected african green monkey Vero 76 cells after 48 to 96 hrs by MTT assay
Cytotoxicity against mock-infected african green monkey Vero 76 cells after 48 to 96 hrs by MTT assay
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[PMID: 25082514] |
2-Ethylbenzimidazole (Compound 20) (5 mg/mL (250 μg); 2-7 days) exhibits antifungal activity against a variety of unicellular and filamentous fungal strains, with the largest inhibition zone diameter (24 mm) observed against Mucor circinelloides RCMB 07328 and Syncephalastrum racemosum RCMB 05922[1].
2-Ethylbenzimidazole (2-3 days) potently inhibits fungal growth, with a minimum MIC of 0.12 μg/mL against Mucor circinelloides RCMB 07328 and an MIC of 0.24 μg/mL against Syncephalastrum racemosum RCMB 05922[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1848-84-6
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Appearance Solid
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Molecular Weight 146.19
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Formula C9H10N2
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Color White to off-white
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SMILES
N=1C=2C=CC=CC2NC1CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Ethylbenzimidazole Related Classifications
HY-W019617 Related Classifications
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