2-Fluoro-5-iodopyridine
Based on 1 Customer Validation
2-Fluoro-5-iodopyridine is an electrolyte additive. 2-Fluoro-5-iodopyridine can not only effectively protect the anode by forming a stable SEI film, but also convert dead lithium into active lithium. 2-Fluoro-5-iodopyridine effectively improves the performance of lithium metal batteries.
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- Pureté : 99.87%
- CAS No.: 171197-80-1
- Formule: C5H3FIN
- Masse moléculaire:222.99
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
2-Fluoro-5-iodopyridine converts dead lithium into active lithium, effectively improving the performance of lithium-metal batteries[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 171197-80-1
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Appearance <33 °C Solid,>37 °C Liquid
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Masse moléculaire 222.99
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Formule C5H3FIN
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Color Off-white to yellow
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SMILES
IC1=CN=C(F)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (448.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (22.42 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (22.42 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4845 mL | 22.4225 mL | 44.8451 mL | 112.1126 mL |
| 5 mM | 0.8969 mL | 4.4845 mL | 8.9690 mL | 22.4225 mL | |
| 10 mM | 0.4485 mL | 2.2423 mL | 4.4845 mL | 11.2113 mL | |
| 15 mM | 0.2990 mL | 1.4948 mL | 2.9897 mL | 7.4742 mL | |
| 20 mM | 0.2242 mL | 1.1211 mL | 2.2423 mL | 5.6056 mL | |
| 25 mM | 0.1794 mL | 0.8969 mL | 1.7938 mL | 4.4845 mL | |
| 30 mM | 0.1495 mL | 0.7474 mL | 1.4948 mL | 3.7371 mL | |
| 40 mM | 0.1121 mL | 0.5606 mL | 1.1211 mL | 2.8028 mL | |
| 50 mM | 0.0897 mL | 0.4485 mL | 0.8969 mL | 2.2423 mL | |
| 60 mM | 0.0747 mL | 0.3737 mL | 0.7474 mL | 1.8685 mL | |
| 80 mM | 0.0561 mL | 0.2803 mL | 0.5606 mL | 1.4014 mL | |
| 100 mM | 0.0448 mL | 0.2242 mL | 0.4485 mL | 1.1211 mL |
2-Fluoro-5-iodopyridine Related Classifications
HY-W007531 Related Classifications
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Keywords
- 2-Fluoro-5-iodopyridine
- 171197-80-1
- Biochemical Assay Reagents
- lithium metal batteries
- dead lithium
- Li||Cu lithium metal battery cells
- SEI layer
- Li||Li symmetrical lithium metal battery cells
- Li||graphite lithium metal battery cells
- lithium anodes
- Li||LiFePO4 lithium metal battery cells
- Li+ diffusion
- solid-electrolyte interphase
- Inhibitor
- inhibitor
- inhibit