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  3. Drug Derivative
  4. 2'-Hydroxyisolupalbigenin

2'-Hydroxyisolupalbigenin (Compound 32) is a prenylated isoflavonoid that can be isolated from the roots of Lupinus albus (Kievskij Mutant).

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2'-Hydroxyisolupalbigenin

2'-Hydroxyisolupalbigenin Chemical Structure

CAS No. : 121747-94-2

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2'-Hydroxyisolupalbigenin Related Antibodies

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Description

2'-Hydroxyisolupalbigenin (Compound 32) is a prenylated isoflavonoid that can be isolated from the roots of Lupinus albus (Kievskij Mutant)[1].

Cellular Effect
Cell Line Type Value Description References
HEK-293T GI
10 %
Compound: 35
Growth inhibition of human HEK293T cells at 10 uM after 24 hrs by MTS assay relative to control
Growth inhibition of human HEK293T cells at 10 uM after 24 hrs by MTS assay relative to control
[PMID: 28522265]
HepG2 IC50
5.66 μM
Compound: 35
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
MCF7 IC50
7.47 μM
Compound: 35
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
SW480 IC50
4.62 μM
Compound: 35
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
Molecular Weight

422.47

Formula

C25H26O6
CAS No.
SMILES

O=C1C(C2=C(O)C(C/C=C(C)\C)=C(O)C=C2)=COC3=C(C/C=C(C)\C)C(O)=CC(O)=C31
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2'-Hydroxyisolupalbigenin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-Hydroxyisolupalbigenin121747-94-2Drug DerivativeDrug derivativeprenylated isoflavonoidLupinus albus
Inhibitorinhibitorinhibit

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2'-Hydroxyisolupalbigenin
Cat. No.:
HY-N10027
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