2-Pyrazinecarboxylic acid
Based on 1 Customer Validation
2-Pyrazinecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 98-97-5
- Formula: C5H4N2O2
- Molecular Weight:124.10
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Pyrazinecarboxylic acid is an active metabolite of pyrazinamide. Pyrazinamidean is an anti-tubercular agent. In this model for the evaluation of the effects of uricosuric agents, the urinary excretion of pyrazinecarboxylic acid was decreased by probenecid and indic ated an inverse correlation between urinary excretion of urate and pyrazinecarboxylic acid. In the in vitro study, the treatment of the vesicles of rat renal brush-border membrane with pyrazinecarboxylic acid produced an increased urate uptake, which was inhibited by uricosuric agents. PZA (pyrazinamide) is con verted to pyrazinecarboxylic acid (POA) in plant cells, suppressing the activity of 1-aminocyclopropane-1-carboxylic acid oxidase (ACO), the enzyme catalysing the final step of ethylene formation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 98-97-5
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Appearance Solid
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Molecular Weight 124.10
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Formula C5H4N2O2
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Color White to off-white
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SMILES
O=C(O)C1=NC=CN=C1
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (402.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 8.0580 mL | 40.2901 mL | 80.5802 mL | 201.4504 mL |
| 5 mM | 1.6116 mL | 8.0580 mL | 16.1160 mL | 40.2901 mL | |
| 10 mM | 0.8058 mL | 4.0290 mL | 8.0580 mL | 20.1450 mL | |
| 15 mM | 0.5372 mL | 2.6860 mL | 5.3720 mL | 13.4300 mL | |
| 20 mM | 0.4029 mL | 2.0145 mL | 4.0290 mL | 10.0725 mL | |
| 25 mM | 0.3223 mL | 1.6116 mL | 3.2232 mL | 8.0580 mL | |
| 30 mM | 0.2686 mL | 1.3430 mL | 2.6860 mL | 6.7150 mL | |
| 40 mM | 0.2015 mL | 1.0073 mL | 2.0145 mL | 5.0363 mL | |
| 50 mM | 0.1612 mL | 0.8058 mL | 1.6116 mL | 4.0290 mL | |
| 60 mM | 0.1343 mL | 0.6715 mL | 1.3430 mL | 3.3575 mL | |
| 80 mM | 0.1007 mL | 0.5036 mL | 1.0073 mL | 2.5181 mL | |
| 100 mM | 0.0806 mL | 0.4029 mL | 0.8058 mL | 2.0145 mL |
2-Pyrazinecarboxylic acid Related Classifications
HY-76353 Related Classifications
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