24-Methylenecycloartanol
Based on 1 publication(s) in Google Scholar
24-Methylenecycloartanol is a compound that can be isolated from Ficus krishnae. 24-Methylenecycloartanol can be used for the research of diabetes.
For research use only. We do not sell to patients.
- Purity : 92.0%
- CAS No.: 1449-09-8
- Formula: C31H52O
- Molecular Weight:440.74
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 24-Methylenecycloartanol
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Raji | IC50 |
8.8 nM
Compound: 3
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Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells after 48 hrs
Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells after 48 hrs
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[PMID: 17503850] |
Chemical Information
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CAS No. 1449-09-8
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Appearance Solid
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Molecular Weight 440.74
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Formula C31H52O
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Color White to off-white
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SMILES
CC1(C)[C@@H](O)CC[C@]2(C3)[C@]43CC[C@]5(C)[C@]([C@H](C)CCC(C(C)C)=C)([H])CC[C@](C)5[C@]4([H])CC[C@@]12[H]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
Protocols
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Research Protocol for Metabolic Diseases
AMP-activated protein kinase, AMPK, is a conserved cellular energy sensor that responds to reduced cellular energy status and coordinates metabolism by increasing ATP-generating catabolic pathways while suppressing ATP-consuming anabolic processes. In metabolic disease research, the AMPK pathway is experimentally relevant because it regulates hepatic lipid synthesis, fatty acid oxidation, glucose production, skeletal-muscle glucose disposal, mTORC1-linked biosynthesis, autophagy, mitochondrial homeostasis, and whole-body energy balance. The central pathway logic is that energy stress, metformin, exercise-like stimulation, or direct AMPK activators increase AMPKα Thr172 phosphorylation and downstream substrate phosphorylation, including ACC and RAPTOR. Phosphorylation of ACC suppresses lipogenesis and supports fatty acid oxidation, whereas phosphorylation of RAPTOR suppresses mTORC1 signaling and links cellular energy status to growth and protein synthesis control. The pathway is linked
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
24-Methylenecycloartanol Related Classifications
HY-N1703 Related Classifications
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