29-Nor-20-oxolupeol
29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM.
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 19891-85-1
- Formula: C29H48O2
- Molecular Weight:428.69
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 25
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Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
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[PMID: 24467317] |
| A549 | IC50 |
>10 μM
Compound: 25
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Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
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[PMID: 24467317] |
| Bel-7402 | IC50 |
>10 μM
Compound: 25
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Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
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[PMID: 24467317] |
| BGC-823 | IC50 |
>10 μM
Compound: 25
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Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
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[PMID: 24467317] |
| BV-2 | IC50 |
6.09 μM
Compound: 25
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
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[PMID: 24467317] |
| HCT-8 | IC50 |
>10 μM
Compound: 25
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Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
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[PMID: 24467317] |
Chemical Information
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CAS No. 19891-85-1
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Appearance Solid
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Molecular Weight 428.69
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Formula C29H48O2
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Color White to off-white
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SMILES
C[C@@]([C@@]1(CC[C@@]2([H])C3(C)C)C)(CC4)[C@@](CC[C@]1([H])[C@]2(CC[C@@H]3O)C)([H])[C@]([C@@H]5C(C)=O)([H])[C@@]4(CC5)C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
29-Nor-20-oxolupeol Related Classifications
HY-N1713 Related Classifications
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