2A/2B Dengue protease substrate acetate
Based on 1 Customer Validation
2A/2B Dengue protease substrate (Ac-RTSKKR-pNA) acetate is a peptide substrate for the Dengue NS2B-NS3 protease, with a Ki value of 12 μM. 2A/2B Dengue protease substrate acetate is used in the development of selective peptide-based inhibitors for the Dengue NS2B-NS3 protease.
For research use only. We do not sell to patients.
- Formula: C39H68N16O11·xC2H4O2
- Molecular Weight:937.06 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 937.06 (free base)
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Formula C39H68N16O11·xC2H4O2
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SMILES
N=C(N)NCCC[C@H](NC(C)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)=O)=O)=O)=O)=O.CC(O)=O.[x]
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Sequence
Ac-Arg-Thr-Ser-Lys-Lys-Arg-{pNA}
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Sequence Shortening
Ac-RTSKKR-{pNA}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)