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  2. Nucleoside Antimetabolite/Analog
  3. (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol 

Cat. No.: HY-W048245 Purity: 98.74%
Handling Instructions Technical Support

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol 화학구조

CAS No. : 190315-43-6

사이즈 가격 재고 수량
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Solution
10 mM * 1 mL in Water 해외재고보유
Oil
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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제품 설명

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

분자량

150.20

화학식

C5H10O3S

CAS No.
Appearance

Oil

Color

Light brown to brown

SMILES

O[C@H]1CS[C@H](CO)[C@H]1O

선적

Room temperature in continental US; may vary elsewhere.

보관
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

H2O : 62.5 mg/mL (416.11 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6578 mL 33.2889 mL 66.5779 mL
5 mM 1.3316 mL 6.6578 mL 13.3156 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.6578 mL 33.2889 mL 66.5779 mL 166.4447 mL
5 mM 1.3316 mL 6.6578 mL 13.3156 mL 33.2889 mL
10 mM 0.6658 mL 3.3289 mL 6.6578 mL 16.6445 mL
15 mM 0.4439 mL 2.2193 mL 4.4385 mL 11.0963 mL
20 mM 0.3329 mL 1.6644 mL 3.3289 mL 8.3222 mL
25 mM 0.2663 mL 1.3316 mL 2.6631 mL 6.6578 mL
30 mM 0.2219 mL 1.1096 mL 2.2193 mL 5.5482 mL
40 mM 0.1664 mL 0.8322 mL 1.6644 mL 4.1611 mL
50 mM 0.1332 mL 0.6658 mL 1.3316 mL 3.3289 mL
60 mM 0.1110 mL 0.5548 mL 1.1096 mL 2.7741 mL
80 mM 0.0832 mL 0.4161 mL 0.8322 mL 2.0806 mL
100 mM 0.0666 mL 0.3329 mL 0.6658 mL 1.6644 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol
Cat. No.:
HY-W048245
수량:
MCE Japan Authorized Agent: