3,3'-Thiodipropanoic acid
Based on 1 Customer Validation
3,3'-Thiodipropanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 111-17-1
- Formula: C6H10O4S
- Molecular Weight:178.20
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E289 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 111-17-1
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Appearance Solid
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Molecular Weight 178.20
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Formula C6H10O4S
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Color White to off-white
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SMILES
O=C(O)CCSCCC(=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (561.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6117 mL | 28.0584 mL | 56.1167 mL | 140.2918 mL |
| 5 mM | 1.1223 mL | 5.6117 mL | 11.2233 mL | 28.0584 mL | |
| 10 mM | 0.5612 mL | 2.8058 mL | 5.6117 mL | 14.0292 mL | |
| 15 mM | 0.3741 mL | 1.8706 mL | 3.7411 mL | 9.3528 mL | |
| 20 mM | 0.2806 mL | 1.4029 mL | 2.8058 mL | 7.0146 mL | |
| 25 mM | 0.2245 mL | 1.1223 mL | 2.2447 mL | 5.6117 mL | |
| 30 mM | 0.1871 mL | 0.9353 mL | 1.8706 mL | 4.6764 mL | |
| 40 mM | 0.1403 mL | 0.7015 mL | 1.4029 mL | 3.5073 mL | |
| 50 mM | 0.1122 mL | 0.5612 mL | 1.1223 mL | 2.8058 mL | |
| 60 mM | 0.0935 mL | 0.4676 mL | 0.9353 mL | 2.3382 mL | |
| 80 mM | 0.0701 mL | 0.3507 mL | 0.7015 mL | 1.7536 mL | |
| 100 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.4029 mL |
3,3'-Thiodipropanoic acid Related Classifications
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