3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione (Standard)
3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione (Standard) is the analytical standard of 3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione. This product is intended for research and analytical applications. Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 1061604-41-8
- Formula: C13H12N2O4
- Molecular Weight:260.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1061604-41-8
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Molecular Weight 260.25
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Formula C13H12N2O4
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SMILES
O=C(C(N(CC1=C2C=CC=C1O)C2=O)CC3)NC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. [Content Brief]
[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)