3-Cyanopropanoic acid
Based on 1 Customer Validation
3-Cyanopropanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 98.40%
- CAS No.: 16051-87-9
- Formula: C4H5NO2
- Molecular Weight:99.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E308 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 16051-87-9
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Appearance Solid
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Molecular Weight 99.09
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Formula C4H5NO2
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Color White to off-white
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SMILES
N#CCCC(=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (1009.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.0918 mL | 50.4592 mL | 100.9184 mL | 252.2959 mL |
| 5 mM | 2.0184 mL | 10.0918 mL | 20.1837 mL | 50.4592 mL | |
| 10 mM | 1.0092 mL | 5.0459 mL | 10.0918 mL | 25.2296 mL | |
| 15 mM | 0.6728 mL | 3.3639 mL | 6.7279 mL | 16.8197 mL | |
| 20 mM | 0.5046 mL | 2.5230 mL | 5.0459 mL | 12.6148 mL | |
| 25 mM | 0.4037 mL | 2.0184 mL | 4.0367 mL | 10.0918 mL | |
| 30 mM | 0.3364 mL | 1.6820 mL | 3.3639 mL | 8.4099 mL | |
| 40 mM | 0.2523 mL | 1.2615 mL | 2.5230 mL | 6.3074 mL | |
| 50 mM | 0.2018 mL | 1.0092 mL | 2.0184 mL | 5.0459 mL | |
| 60 mM | 0.1682 mL | 0.8410 mL | 1.6820 mL | 4.2049 mL | |
| 80 mM | 0.1261 mL | 0.6307 mL | 1.2615 mL | 3.1537 mL | |
| 100 mM | 0.1009 mL | 0.5046 mL | 1.0092 mL | 2.5230 mL |
3-Cyanopropanoic acid Related Classifications
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