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Art. -Nr.: HY-172223

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3-Deazaguanosine

(Synonyms: C3Guo)

3-Deazaguanosine (C3Guo) has potent antiviral activity against SARS-CoV-2 (EC₅₀: 1.14 μM, CC₅₀: >200 μM for Vero E6 cells). 3-Deazaguanosine prevents COVID-19 pneumonia.

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CAS. Nr.: 56039-11-3
Formel: C₁₁H₁₄N₄O₅
Molecular Weight:282.25

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

3-Deazaguanosine Chemical Structure

CAS. Nr.: 56039-11-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

3-Deazaguanosine (C3Guo) has potent antiviral activity against SARS-CoV-2 (EC₅₀: 1.14 μM, CC₅₀: >200 μM for Vero E6 cells). 3-Deazaguanosine prevents COVID-19 pneumonia^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	ED₅₀	7 μM Compound: 9-DGR	Effective dose that produced 50% inhibition of L1210 Leukemia cell growth in culture Effective dose that produced 50% inhibition of L1210 Leukemia cell growth in culture	[PMID: 6827548]

Chemical Information

CAS. Nr. 56039-11-3
Molecular Weight 282.25
Formel C₁₁H₁₄N₄O₅
SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2C=C(N)NC3=O)O[C@@H]1CO
Synonyms

C3Guo
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Saito-Tarashima N, et al. 3-Deazaguanosine inhibits SARS-CoV-2 viral replication and reduces the risk of COVID-19 pneumonia in hamster. iScience. 2025 Mar 1;28(4):112140. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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