2. PROTAC
  3. PROTAC Linkers
  4. 4-(2-Bromoethyl)phenol

4-(2-Bromoethyl)phenol is a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

4-(2-Bromoethyl)phenol

4-(2-Bromoethyl)phenol Chemical Structure

CAS No. : 14140-15-9

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4-(2-Bromoethyl)phenol Related Antibodies

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Description

4-(2-Bromoethyl)phenol is a PROTAC linker that can be used in the synthesis of PROTACs.

Cellular Effect
Cell Line Type Value Description References
B16 IC50
32 μM
Compound: 1c
Tested in vitro for cytotoxicity against B16 cell line in murine melanoma activity expressed in IC50
Tested in vitro for cytotoxicity against B16 cell line in murine melanoma activity expressed in IC50
10.1016/0960-894X(95)00310-P
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E333 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-(2-Bromoethyl)phenol Related Antibodies
Molecular Weight

201.06

Formula

C8H9BrO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

BrCCC1=CC=C(O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation

Purity: 97.92%

SDS (393 KB)

COA (243 KB)

Handling Instructions (2659 KB)
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4-(2-Bromoethyl)phenol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-(2-Bromoethyl)phenol14140-15-9PROTAC LinkersInhibitorinhibitorinhibit

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4-(2-Bromoethyl)phenol
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