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Cat. No.: HY-W004888

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4-(2-Bromoethyl)phenol

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4-(2-Bromoethyl)phenol is a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

CAS No.: 14140-15-9
Formula: C₈H₉BrO
Molecular Weight:201.06

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

4-(2-Bromoethyl)phenol Chemical Structure

CAS No.: 14140-15-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- Cellular Effect
- In Vitro
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Biological Activity

Description

4-(2-Bromoethyl)phenol is a PROTAC linker that can be used in the synthesis of PROTACs.

All PROTAC Linkers Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
B16	IC₅₀	32 μM Compound: 1c	Tested in vitro for cytotoxicity against B16 cell line in murine melanoma activity expressed in IC50 Tested in vitro for cytotoxicity against B16 cell line in murine melanoma activity expressed in IC50	10.1016/0960-894X(95)00310-P

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E333 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.