2. Autophagy Others
  3. Autophagy Drug Derivative
  4. 4E1RCat 17d

4E1RCat 17d (Compound 17d) is a derivative of the ATG5 inhibitor lead compound T1742. 4E1RCat 17d shows no activity against the interactions of ATG5-ATG16L1 and ATG5-TECAIR. 4E1RCat 17d induces Autophagy inhibition.

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4E1RCat 17d

4E1RCat 17d Chemical Structure

CAS No. : 2841473-92-3

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4E1RCat 17d Related Antibodies

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Description

4E1RCat 17d (Compound 17d) is a derivative of the ATG5 inhibitor lead compound T1742. 4E1RCat 17d shows no activity against the interactions of ATG5-ATG16L1 and ATG5-TECAIR. 4E1RCat 17d induces Autophagy inhibition[1].

In Vitro

4E1RCat 17d shows no obvious inhibitory activity against the ATG5−ATG16L1 and ATG5−TECAIR interactions in a cell-free HTRF binding assay[1].
4E1RCat 17d (20 μM; 6 h) inhibits autophagy in COS-7 cells, reducing autophagy incidence to 20.01%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4E1RCat 17d Related Antibodies

Cell Autophagy Assay[1]

Cell Line: COS-7 cells
Concentration: 20 μM
Incubation Time: 6 h
Result: Reduced autophagy incidence in COS-7 cells to 20.01%.
Molecular Weight

504.53

Formula

C31H24N2O5
CAS No.
SMILES

CC(NC1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=C1)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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4E1RCat 17d Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4E1RCat 17d2841473-92-3AutophagyDrug DerivativeDrug derivativemammalian cellsTECAIRATG16L1autophagyCOS-7 cellsATG5Inhibitorinhibitorinhibit

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