5-CITEP
5 CITEP is a potent HIV integrase inhibitor; its IC50s by multiple MIA and MPA are 2.3 ± 0.1 μM and 2.1 ± 0.1 μM, respectively.
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- CAS No.: 900779-63-7
- Formule: C12H8ClN5O2
- Masse moléculaire:289.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 900779-63-7
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Masse moléculaire 289.68
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Formule C12H8ClN5O2
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SMILES
O=C(C=C(O)C1=NN=NN1)C2=CC=3C=C(Cl)C=CC3N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Goldgur Y, et al. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13040-3. [Content Brief]
[2]. Johnson AA, et al. Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop. J Biol Chem. 2006 Jan 6;281(1):461-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-CITEP Related Classifications
HY-50693 Related Classifications
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