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Cat. No.: HY-129983R

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5-Hydroxymethyl-2'-deoxyuridine (Standard)

Name: 5-Hydroxymethyl-2'-deoxyuridine (Standard)
Brand: MedChemExpress
SKU: HY-129983R
Price: 75.00 USD
Availability: InStock
Rating: 5 (1 reviews)

5-Hydroxymethyl-2'-deoxyuridine (Standard) is the analytical standard of 5-Hydroxymethyl-2'-deoxyuridine. This product is intended for research and analytical applications. 5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 5116-24-5
Formula: C₁₀H₁₄N₂O₆
Molecular Weight:258.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-Hydroxymethyl-2'-deoxyuridine (Standard) Chemical Structure

CAS No.: 5116-24-5

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 5116-24-5
Molecular Weight 258.23
Formula C₁₀H₁₄N₂O₆
SMILES

O[C@H]1C[C@H](N2C(NC(C(CO)=C2)=O)=O)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Shiau GT, et al. Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogues. J Med Chem. 1980 Feb;23(2):127-33. [Content Brief]

[2]. Kahilainen LI, et al. 5-Hydroxymethyl-2'-deoxyuridine. Cytotoxicity and DNA incorporation studied by using a novel [2-14C]-derivative with normal and leukemic human hematopoietic cells. Acta Chem Scand B. 1985;39(6):477-84. [Content Brief]

[3]. JA Vilpo, et al. 5-Hydroxymethyl-2′-Deoxyuridine: Studies of Antileukemic Properties in Vitro and in Vivo. Nucleosides and Nucleotides . 1987.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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5-Hydroxymethyl-2'-deoxyuridine (Standard)

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5-Hydroxymethyl-2'-deoxyuridine (Standard)