5-Iodopent-1-yne
Based on 1 Customer Validation
5-Iodopent-1-yne (5-Iodo-1-pentyne) is a PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté : ≥95.0%
- CAS No.: 2468-55-5
- Formule: C5H7I
- Masse moléculaire:194.02
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E415 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2468-55-5
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Appearance Liquid
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Masse moléculaire 194.02
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Formule C5H7I
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Color Colorless to light yellow
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SMILES
ICCCC#C
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Synonyms
5-Iodo-1-pentyne
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (515.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (239 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1541 mL | 25.7705 mL | 51.5411 mL | 128.8527 mL |
| 5 mM | 1.0308 mL | 5.1541 mL | 10.3082 mL | 25.7705 mL | |
| 10 mM | 0.5154 mL | 2.5771 mL | 5.1541 mL | 12.8853 mL | |
| 15 mM | 0.3436 mL | 1.7180 mL | 3.4361 mL | 8.5902 mL | |
| 20 mM | 0.2577 mL | 1.2885 mL | 2.5771 mL | 6.4426 mL | |
| 25 mM | 0.2062 mL | 1.0308 mL | 2.0616 mL | 5.1541 mL | |
| 30 mM | 0.1718 mL | 0.8590 mL | 1.7180 mL | 4.2951 mL | |
| 40 mM | 0.1289 mL | 0.6443 mL | 1.2885 mL | 3.2213 mL | |
| 50 mM | 0.1031 mL | 0.5154 mL | 1.0308 mL | 2.5771 mL | |
| 60 mM | 0.0859 mL | 0.4295 mL | 0.8590 mL | 2.1475 mL | |
| 80 mM | 0.0644 mL | 0.3221 mL | 0.6443 mL | 1.6107 mL | |
| 100 mM | 0.0515 mL | 0.2577 mL | 0.5154 mL | 1.2885 mL |
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