5-Oxo Pitavastatin
5-Oxo Pitavastatin (M-3) is the metabolite of Pitavastatin (HY-B0144A). Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects.
For research use only. We do not sell to patients.
- CAS No.: 222306-15-2
- Formula: C25H22FNO4
- Molecular Weight:419.44
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 222306-15-2
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Appearance Oil
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Molecular Weight 419.44
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Formula C25H22FNO4
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SMILES
O=C(O)C[C@H](O)CC(/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (238.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3841 mL | 11.9207 mL | 23.8413 mL | 59.6033 mL |
| 5 mM | 0.4768 mL | 2.3841 mL | 4.7683 mL | 11.9207 mL | |
| 10 mM | 0.2384 mL | 1.1921 mL | 2.3841 mL | 5.9603 mL | |
| 15 mM | 0.1589 mL | 0.7947 mL | 1.5894 mL | 3.9736 mL | |
| 20 mM | 0.1192 mL | 0.5960 mL | 1.1921 mL | 2.9802 mL | |
| 25 mM | 0.0954 mL | 0.4768 mL | 0.9537 mL | 2.3841 mL | |
| 30 mM | 0.0795 mL | 0.3974 mL | 0.7947 mL | 1.9868 mL | |
| 40 mM | 0.0596 mL | 0.2980 mL | 0.5960 mL | 1.4901 mL | |
| 50 mM | 0.0477 mL | 0.2384 mL | 0.4768 mL | 1.1921 mL | |
| 60 mM | 0.0397 mL | 0.1987 mL | 0.3974 mL | 0.9934 mL | |
| 80 mM | 0.0298 mL | 0.1490 mL | 0.2980 mL | 0.7450 mL | |
| 100 mM | 0.0238 mL | 0.1192 mL | 0.2384 mL | 0.5960 mL |