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Cat. No.: HY-164568

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7β,16α-Dihydroxybufalin

7β,16α-Dihydroxybufalin is a dihydroxylated derivative of bufalin, which exhibits cytotoxicities against cancer cell lines.

For research use only. We do not sell to patients.

CAS No.: 773133-78-1
Formula: C₂₄H₃₄O₆
Molecular Weight:418.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

7β,16α-Dihydroxybufalin Chemical Structure

CAS No.: 773133-78-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

7β,16α-Dihydroxybufalin is a dihydroxylated derivative of bufalin, which exhibits cytotoxicities against cancer cell lines^[1]^[2].

Chemical Information

CAS No. 773133-78-1
Molecular Weight 418.52
Formula C₂₄H₃₄O₆
SMILES

O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@@H](C(C=C4)=COC4=O)[C@@H](C2)O)C)([H])[C@@]5([C@](C[C@H](CC5)O)([H])C[C@@H]3O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ye M, et al. Novel cytotoxic bufadienolides derived from bufalin by microbial hydroxylation and their structure-activity relationships. J Steroid Biochem Mol Biol. 2004 Jun;91(1-2):87-98. [Content Brief]

[2]. Li K, et al. Enzymatic synthesis of bufadienolide O‐glycosides as potent antitumor agents using a microbial glycosyltransferase[J]. Advanced Synthesis & Catalysis, 2017, 359(21): 3765-3772.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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