8-Arm-PEG10000-Acrylate
8-Arm-PEG10000-Acrylate (8-Arm-PEG10000-AC) is an eight-arm PEG derivative. The core structure of 8-Arm-PEG10000-Acrylate consists of eight PEG chains, each modified at the end with an acrylate (acrylate) group. 8-Arm-PEG10000-Acrylate can be used for research on hydrogel preparation and drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 2111799-19-8
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
In Vitro
The structure of PEG-Acrylate comprises two key components that work synergistically:
Acrylate: A key monomer in photopolymerization or thermal polymerization, it can react with other acrylate groups through free radical polymerization to form a covalently cross-linked network.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2111799-19-8
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SMILES
C=CC(OCCOCC(COCCOC(C=C)=O)(COCCOC(C=C)=O)COCC(COCCOC(C=C)=O)(COCCOC(C=C)=O)COCC(COCCOC(C=C)=O)(COCCOC(C=C)=O)COCCOC(C=C)=O)=O.[n].[n].[n].[n].[n].[n].[n].[n]
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Synonyms
8-Arm-PEG10000-AC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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3D Hydrogel Synthetic Scaffold Culture
3D hydrogel synthetic scaffold culture embeds cells, spheroids, organoids, or tissue fragments inside a hydrated crosslinked polymer network so that cells receive matrix and cell-cell cues in three dimensions rather than from a flat plastic surface. A literature-supported model protocol is PEG-4MAL hydrogel culture, in which four-arm maleimide-terminated PEG is functionalized with cysteine-containing adhesive peptides such as RGD and crosslinked with protease-degradable peptides such as GPQ-W; this creates a defined, modular scaffold that supports human organoid generation and culture. The readouts are scaffold-supported growth, morphology, lumen formation, budding, viability, proliferation, lineage-marker expression, and matrix-dependent expansion or differentiation; reported assays include transmitted-light imaging, immunofluorescence, in situ hybridization, qRT-PCR, and rheological characterization.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Arm-PEG10000-Acrylate Related Classifications
HY-182837 Related Classifications
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