8-Bromoguanosine-13C2,15N
8-Bromoguanosine-13C2,15N is the 13C- and 15N-labeled 8-Bromoguanosine (HY-W019033). 8-Bromoguanosine is a purine nucleoside, a brominated derivative of guanosine. 8-Bromoguanosine can reduce the conformational heterogeneity of RNA to enhance its function.
For research use only. We do not sell to patients.
- Formula: C813C2H12BrN415NO5
- Molecular Weight:365.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 4016-63-1
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Molecular Weight 365.12
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Formula C813C2H12BrN415NO5
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SMILES
O[C@H]1[C@H]([C@@H](O[C@@H]1CO)N2[13C](N=C(N3)N)=[13C]([15N]=C2Br)C3=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Goodman MG, Weigle WO. Intracellular lymphocyte activation and carrier-mediated transport of C8-substituted guanine ribonucleosides. Proc Natl Acad Sci U S A. 1984 Feb;81(3):862-6. [Content Brief]
[2]. Koo GC, Jewell ME, Manyak CL, Sigal NH, Wicker LS. Activation of murine natural killer cells and macrophages by 8-bromoguanosine. J Immunol. 1988 May 1;140(9):3249-52. [Content Brief]
[3]. Yajima R, et al. A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme. Chem Biol. 2007 Jan;14(1):23-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Bromoguanosine-13C2,15N Related Classifications
HY-W747965 Related Classifications
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