8-Chlorotheophylline-d₆

Name: 8-Chlorotheophylline-d 6
Brand: MedChemExpress
SKU: HY-W014203S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W014203S Purity: 99.83%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

8-Chlorotheophylline-d₆ (8-Chlorotheophylline-d₆) is the deuterium-labeled 8-Chlorotheophylline (HY-W014203). 8-Chlorotheophylline is an organic compound.

For research use only. We do not sell to patients.

8-Chlorotheophylline-d<sub>6</sub> Chemical Structure

8-Chlorotheophylline-d₆ Chemical Structure

CAS No. : 1346598-95-5

Size	Price	Stock	Quantity
1 mg	USD 280	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 620	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 980	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

8-Chlorotheophylline-d₆ (8-Chlorotheophylline-d₆) is the deuterium-labeled 8-Chlorotheophylline (HY-W014203)^[1]. 8-Chlorotheophylline is an organic compound.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

220.65

Formula

C₇HD₆ClN₄O₂

CAS No.

1346598-95-5

Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=C(N=C(N2)Cl)N(C(N1C([2H])([2H])[2H])=O)C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (113.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5321 mL	22.6603 mL	45.3206 mL
5 mM	0.9064 mL	4.5321 mL	9.0641 mL
10 mM	0.4532 mL	2.2660 mL	4.5321 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.83%

Select Batch:

Data Sheet (274 KB) SDS (0 KB)

COA (254 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.5321 mL	22.6603 mL	45.3206 mL	113.3016 mL
	5 mM	0.9064 mL	4.5321 mL	9.0641 mL	22.6603 mL
	10 mM	0.4532 mL	2.2660 mL	4.5321 mL	11.3302 mL
	15 mM	0.3021 mL	1.5107 mL	3.0214 mL	7.5534 mL
	20 mM	0.2266 mL	1.1330 mL	2.2660 mL	5.6651 mL
	25 mM	0.1813 mL	0.9064 mL	1.8128 mL	4.5321 mL
	30 mM	0.1511 mL	0.7553 mL	1.5107 mL	3.7767 mL
	40 mM	0.1133 mL	0.5665 mL	1.1330 mL	2.8325 mL
	50 mM	0.0906 mL	0.4532 mL	0.9064 mL	2.2660 mL
	60 mM	0.0755 mL	0.3777 mL	0.7553 mL	1.8884 mL
	80 mM	0.0567 mL	0.2833 mL	0.5665 mL	1.4163 mL
	100 mM	0.0453 mL	0.2266 mL	0.4532 mL	1.1330 mL