9,10-Didehydroeffususol A
9,10-Didehydroeffususol A is a natural phenolic compound.
For research use only. We do not sell to patients.
- CAS No.: 1869082-57-4
- Formula: C18H18O3
- Molecular Weight:282.33
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
11.1 μM
Compound: 85
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced nitric oxide production
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced nitric oxide production
|
[PMID: 29280630] |
| RAW264.7 | IC50 |
16.3 μM
Compound: 85
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced nitric oxide production
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced nitric oxide production
|
[PMID: 29280630] |
9,10-Didehydroeffususol A (6.25-100 µM; 4–48 h) exhibits significant cytotoxic activity against several human cancer cell lines[1].
9,10-Didehydroeffususol A (3-50 µM; 12–24 h) inhibits LPS-induced NO production in mouse macrophage RAW 264.7 cells (IC50 = 11.10 µM) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:SHSY-5Y, SMMC-7721, HepG-2, Hela, MCF-7
-
Concentration:6.25-100 μM (treatment); 10 μL (CCK-8)
-
Incubation Time:48 h (treatment); 4 h (CCK-8)
-
Result:Inhibited proliferation of SHSY-5Y with IC₅₀=31.98 μM, SMMC-7721 with IC₅₀=42.94 μM, HepG-2 with IC₅₀=37.03 μM, Hela with IC₅₀=52.82 μM, and MCF-7 with IC₅₀=10.87 μM.
Chemical Information
-
CAS No. 1869082-57-4
-
Molecular Weight 282.33
-
Formula C18H18O3
-
SMILES
OC1=CC=C2C3=C(C(OC)C)C=C(O)C=C3C=CC2=C1C
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
9,10-Didehydroeffususol A Related Classifications
HY-N7712 Related Classifications
Powered by Bioz