Linoleoyl-CoA

Linoleoyl-CoA (Linoleoyl Coenzyme A) (0-200 μM; 15-30 min) as the donor substrate results in sn-glycerol-3-phosphate acyltransferase activity that is 6-fold higher in neonatal rabbit skeletal muscle sarcoplasmic reticulum (1.4 nmol 18:2/min per mg) than in adult rabbit skeletal muscle sarcoplasmic reticulum (0.22 nmol 18:2/min per mg), with identical K_m values for glycerol 3-phosphate (0.3 mM) and linoleoyl-CoA (75 μM) between the two membrane types^[1].
Linoleoyl-CoA (0-200 μM; 15 min) as the donor substrate results in lysophosphatidylcholine acyltransferase activity that is identical in neonatal and adult rabbit skeletal muscle sarcoplasmic reticulum, with a maximum specific activity of 4-5 nmol 18:2/min per mg and identical K_m values for L-α-lysophosphatidylcholine (75 μM) and linoleoyl-CoA (50-70 μM)^[1].
Linoleoyl-CoA (100 μM; 15 min) as the donor substrate results in both sn-glycerol-3-phosphate acyltransferase and lysophosphatidylcholine acyltransferase activities that are higher in neonatal rabbit skeletal muscle sarcolemma (1.64 nmol 18:2/min per mg and 18.9 nmol 18:2/min per mg, respectively) than in adult rabbit skeletal muscle sarcolemma (0.22 nmol 18:2/min per mg and 8.53 nmol 18:2/min per mg, respectively)^[1].
Linoleoyl-CoA (1-5 min) incubation of developing safflower seed microsomes with [1-¹⁴C] oleoyl-CoA in the presence of 3 μmol/mL NADH produces no detectable linoleoyl-CoA at 1 min, 2 min, or 5 min of incubation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.