カンタキサンチン
Based on 4 publication(s) in Google Scholar
Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 514-78-3
- 分子式: C40H52O2
- 分子量:564.84
-
保管条件:
-20°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-B2163
AstaxanthinAntioxidant -
HY-120318
ZeaxanthinDiet-obtained Carotenoid -
HY-N0411
β-CaroteneCarotenoid compound -
HY-N6947
LuteinAnti-inflammatory Agent -
HY-N2302
FucoxanthinMarine Carotenoid -
HY-N0287
LycopeneAntioxidant -
HY-N6677
β-Apo-8'-carotenalCYP1A Inducer -
HY-N2302R
Fucoxanthin (Standard)Marine Carotenoid -
HY-N0411R
β-Carotene (Standard)Carotenoid compound -
HY-108059
β-CryptoxanthinCarotenoid -
HY-B1960R
Canthaxanthin (Standard)Antioxidant -
HY-D0249
Sunset Yellow FCFAzo Dye
MedChemExpress（MCE）の使用を引用している文献 Canthaxanthin
MoreEndogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
IC50 & Target
|
Human Endogenous Metabolite |
体外実験
Canthaxanthin enrichment of LDL has the potential to protect cholesterol from oxidation. In addition to its free radical scavenging and antioxidant properties (e.g., the induction of catalase and superoxide dismutase), canthaxanthin shows immunomodulatory activity (e.g. enhancing the proliferation and function of immune competent cells) and plays important role in gap junction communication (e.g. induction of the transmembrane protein connexin)[1]. At concentrations of 0.1 to 1 x 1000 μM, canthaxanthin significantly reduces the overall number of tumor cells. The greatest inhibition is observed at a canthaxanthin concentration of 1000 after 72 h and 96 h of incubation[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 514-78-3
-
性状 Solid
-
分子量 564.84
-
分子式 C40H52O2
-
Color Reddish brown to black
-
SMILES
CC(/C=C/C(C(C)(CCC1=O)C)=C1C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C(C(C)(CCC2=O)C)=C2C
-
別名
Canthaxanthin; E 161g; all-trans-Canthaxanthin
-
Structure Classification
-
Initial Source
-
輸送条件
Shipping with dry ice.
-
保管条件
-20°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Publications (4)
-
Journal Impact Factor
-
Most Recent
-
Int Immunopharmacol
2025 Feb 6:147:113975. PMID: 39787760 -
FASEB J
Activation of TMEM16A by natural product canthaxanthin promotes gastrointestinal contraction. [Abstract]2020 Oct;34(10):13430-13444. PMID: 32812278 -
-
Biochem Biophys Res Commun
Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. [Abstract]2018 Sep 3;503(1):297-303. PMID: 29890135
溶剤 & 溶解度
体外:
DMSO : 2 mg/mL (3.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (271 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Esatbeyoglu T, et al. Canthaxanthin: From molecule to function. Mol Nutr Food Res. 2017 Jun;61(6). [Content Brief]
[2]. Huang DS, et al. Inhibitory effects of canthaxanthin on in vitro growth of murine tumor cells. Cancer Lett. 1992 Aug 31;65(3):209-13. [Content Brief]
[3]. Palozza P, et al. Canthaxanthin supplementation alters antioxidant enzymes and iron concentration in liver of Balb/c mice. J Nutr. 2000 May;130(5):1303-8. [Content Brief]
[4]. Chew BP, et al. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53. [Content Brief]
[5]. Grubbs CJ, et al. Effect of canthaxanthin on chemically induced mammary carcinogenesis. Oncology. 1991;48(3):239-45. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7704 mL | 8.8521 mL | 17.7041 mL | 44.2603 mL |
Canthaxanthin 関連分類
HY-B1960 関連分類
Powered by Bioz