1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. D2343

D2343 

Cat. No.: HY-U00206
Handling Instructions

D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.

For research use only. We do not sell to patients.

D2343 Chemical Structure

D2343 Chemical Structure

CAS No. : 72734-63-5

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Description

D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.

IC50 & Target

β2-adrenoceptor[1]
α1- adrenoceptor[1]

In Vitro

D2343 is a compound with about the same beta 2-adrenoceptor-agonist effect as Terbutaline and exhibiting in addition an alpha 1-receptor inhibitory activity[1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

D2343 has been compared to the beta 2-agonist Terbutaline on oestrogenized uterine preparations from rat and rabbit and in myometrial strips from homo. D2343 has shown an ability to relax the uterine muscles to the same degree as Terbutaline or even more, especially when the two drugs are compared in preparations from rabbit and rat[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

329.43

Formula

C₂₀H₂₇NO₃

CAS No.

72734-63-5

SMILES

OC(C1=CC=C(O)C=C1)CNC(C)(C)CCC2=C(C=CC=C2)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

D2343D 2343D-2343Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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