Pomalidomide-PEG4-Ph-NH2
Based on 1 Customer Validation
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
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- Pureté : 98.0%
- CAS No.: 1818885-63-0
- Formule: C27H32N4O8
- Masse moléculaire:540.57
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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HY-21930
Pomalidomide-PEG4-C-COOHE3 Ligase Ligand-Linker Conjugate -
HY-115560A
Thalidomide-O-amido-C3-NH2 TFAE3 Ligase Ligand-Linker Conjugates -
HY-103613
Thalidomide-O-amido-C4-NH2 TFAE3 ligase ligand-linker conjugate -
HY-103611
Thalidomide-O-amido-PEG3-C2-NH2 TFAE3 ligase ligand-linker conjugate -
HY-103614
Thalidomide-O-amido-C8-NH2 TFAE3 Ligase Ligand-Linker Conjugate -
HY-103600
(S,R,S)-AHPC-PEG1-N3E3 Ligase Ligand-Linker Conjugate -
HY-103604
(S,R,S)-AHPC-PEG4-NH2 hydrochlorideE3 ligase ligand-linker conjugate -
HY-103604A
(S,R,S)-AHPC-PEG4-NH2E3 ligase ligand-linker conjugate -
HY-103596
Thalidomide-4-OHCereblon Ligand -
HY-103601
(S,R,S)-AHPC-PEG4-N3E3 ligase ligand-linker conjugate -
HY-103602
(S,R,S)-AHPC-PEG3-NH2 hydrochlorideE3 Ligase Ligand-Linker Conjugate -
HY-103603
(S,R,S)-AHPC-PEG2-NH2 hydrochlorideE3 ligase ligand-linker conjugate
Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates
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Activité biologique
Description
IC50 & Target
[1]|
Cereblon |
Chemical Information
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CAS No. 1818885-63-0
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Appearance Solid
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Masse moléculaire 540.57
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Formule C27H32N4O8
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Color Light yellow to yellow
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOC4=CC=C(N)C=C4)=O
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Synonyms
Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (92.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8499 mL | 9.2495 mL | 18.4990 mL | 46.2475 mL |
| 5 mM | 0.3700 mL | 1.8499 mL | 3.6998 mL | 9.2495 mL | |
| 10 mM | 0.1850 mL | 0.9249 mL | 1.8499 mL | 4.6247 mL | |
| 15 mM | 0.1233 mL | 0.6166 mL | 1.2333 mL | 3.0832 mL | |
| 20 mM | 0.0925 mL | 0.4625 mL | 0.9249 mL | 2.3124 mL | |
| 25 mM | 0.0740 mL | 0.3700 mL | 0.7400 mL | 1.8499 mL | |
| 30 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5416 mL | |
| 40 mM | 0.0462 mL | 0.2312 mL | 0.4625 mL | 1.1562 mL | |
| 50 mM | 0.0370 mL | 0.1850 mL | 0.3700 mL | 0.9249 mL | |
| 60 mM | 0.0308 mL | 0.1542 mL | 0.3083 mL | 0.7708 mL | |
| 80 mM | 0.0231 mL | 0.1156 mL | 0.2312 mL | 0.5781 mL |
Pomalidomide-PEG4-Ph-NH2 Related Classifications
HY-41549 Related Classifications
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