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- Ondetia linearis Benth.
Ondetia linearis Benth.
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Ondetia linearis Benth. (7)
- Formula: C21H22O4
- Molecular Weight: 338.40
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation. 4-Hydroxyderricin is promising for research of inflammatory diseases.
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- Formula: C25H28O4
- Molecular Weight: 392.49
Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells.
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- Formula: C15H12O4
- Molecular Weight: 256.26
(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is a dihydroflavone flavonoid. (±)-Liquiritigenin is isolated from the aerial parts of Angelica keiskei. (±)-Liquiritigenin reduces LDH release in cells. (±)-Liquiritigenin exerts a cytoprotective effect against glucose oxidase-induced cellular oxidative stress. (±)-Liquiritigenin exhibits a tumor-promoting effect in liver cancer.
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- Formula: C26H30O4
- Molecular Weight: 406.52
Xanthoangelol F is a prenylated (geranylated) chalcone and Antibacterial agent. Xanthoangelol F can be isolated from Angelica keiskei. Xanthoangelol F inhibits the growth of Gram-positive bacteria Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus, with an MIC of 64 μg/mL.
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- Formula: C20H22O4
- Molecular Weight: 326.39
Uncinatone is a natural product.
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- Formula: C10H16O4
- Molecular Weight: 200.23
5-O-Ethylcleroindicin D is a natural product.
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- Formula: C32H48O15
- Molecular Weight: 672.71
19-OD-Carboxyglucopyranosyl-12-O--D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene was isolated from the acetone-soluble extract of Clerodendrum bungei roots.
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