Appendicula reflexa Blume
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Appendicula reflexa Blume (1)
Coelonin
- Formula: C15H14O3
- Molecular Weight: 242.27
Coelonin is a dihydrophenanthrene with anti-inflammation activity. Coelonin inhibits LPS-induced PTEN phosphorylation. Coelonin inhibits NF-κB activation and p27Kip1 degradation by regulating the PI3K/AKT pathway negatively. Coelonin can inhibit IκBα phosphorylation and degradation and increases the expression of IκBα protein.
