Forsythia koreana (Rehder) Nakai
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Forsythia koreana (Rehder) Nakai (1)
rel-Cleroindicin F
Cat. No.: HY-N3602A
CAS No.: 94535-01-0
Synonyms: Rengyolone
- Formula: C8H10O3
- Molecular Weight: 154.16
rel-Cleroindicin F (Rengyolone) is a cyclohexyl acetyl compound that can be isolated from the fruit of forsythia and has anti-inflammatory activity. It strongly inhibits the production of nitric oxide (NO) and tumor necrosis factor-alpha (TNF-α). rel-Cleroindicin F does this by downregulating the activity of NF-κB and NF-κB kinases in RAW 264.7 cells stimulated by LPS (HY-D1056), thus inhibiting the expression of inducible nitric oxide synthase (NO Synthase) and nitric oxide production.
