1. GPCR/G Protein
    Neuronal Signaling
  2. Neurokinin Receptor
  3. Neurokinin A(4-10)

Neurokinin A(4-10) 

Cat. No.: HY-P0236
Handling Instructions

Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Neurokinin A(4-10) Chemical Structure

Neurokinin A(4-10) Chemical Structure

CAS No. : 97559-35-8

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Other In-stock Forms of Neurokinin A(4-10):

Other Forms of Neurokinin A(4-10):

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Description

Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.

IC50 & Target

NK2 receptor[1]

In Vitro

Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].

Molecular Weight

766.91

Formula

C₃₄H₅₄N₈O₁₀S

CAS No.

97559-35-8

Sequence

Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

Sequence Shortening

DSFVGLM-NH2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Neurokinin A(4-10)
Cat. No.:
HY-P0236
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