Neurokinin A(4-10)
Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.
For research use only. We do not sell to patients.
- CAS No.: 97559-35-8
- Formula: C34H54N8O10S
- Molecular Weight:766.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
NK2 receptor[1]
Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 97559-35-8
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Molecular Weight 766.91
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Formula C34H54N8O10S
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Sequence
Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
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Sequence Shortening
DSFVGLM-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)