1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-159565
    VEGFR-2/InhA-IN-1
    Inhibitor
    VEGFR-2/InhA-IN-1 is a pyrazole-based dual inhibitor of InhA-VEGFR with anti-tuberculosis and anti-angiogenic activities. VEGFR-2/InhA-IN-1 has good antibacterial activity against Mycobacterium tuberculosis H37Rv strain (MIC=6.25 μg/mL) and significantly inhibits VEGFR-2 (IC50=15.27 nM).
    VEGFR-2/InhA-IN-1
  • HY-149679
    PROTAC eDHFR Degrader-2
    Inhibitor
    PROTAC eDHFR Degrader-2 (compound 7b) is a potent degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), enabling robust degradation of eDHFR-tagged proteins.
    PROTAC eDHFR Degrader-2
  • HY-W115276
    Fenticonazole
    Fenticonazole is an imidazole derivative with antibacterial and antifungal activity. Fenticonazole has the potential for the research of mixed vaginitis.
    Fenticonazole
  • HY-W004282S2
    Undecanoic acid-d2
    Inhibitor
    Undecanoic acid-d2 (Undecanoate-d2) is the deuterium labeled Undecanoic acid (HY-W004282). Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid-d<sub>2</sub>
  • HY-113627A
    Undecylprodigiosin hydrochloride
    Inhibitor
    Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities.
    Undecylprodigiosin hydrochloride
  • HY-W355141
    Isopulegol
    Isopulegol is one of the main components of ECO (Eucalyptus citriodora oil). ECO has antibacterial activity.
    Isopulegol
  • HY-P11657
    GN-2 peptoid
    Inhibitor
    GN-2 peptoid is a 9-mer cationic amphipathic peptoid and bactericidal agent with an overall net charge of +4, broad-spectrum antimicrobial activity, and low hemolytic and cytotoxic activity against mammalian cells. GN-2 peptoid exerts bactericidal action against Escherichia coli in a concentration-dependent manner. GN-2 peptoid exhibits antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, Pseudomonas aeruginosa strains. GN-2 peptoid shows low toxicity against human red blood cells and HeLa cells. GN-2 peptoid maintains antimicrobial activity in the presence of 50% human blood plasma. GN-2 peptoid can be used for the research of bacterial infections.
    GN-2 peptoid
  • HY-145417
    G092
    G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter. Transmembrane ATP-binding cassette (ABC) transporters are crucial cellular machines that move molecules small and large across membranes. G092 has the potential for the research of antimicrobial agents.
    G092
  • HY-N7321A
    (R)-Eucomol
    Inhibitor
    (R)-Eucomol, a flavonoid derivative, displays marginal antibacterial activity. (R)-Eucomol shows cytotoxic activity against KB and P-388 cells.
    (R)-Eucomol
  • HY-P3349
    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]
    Inhibitor
    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively.
    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]
  • HY-113595
    Temafloxacin hydrochloride
    Inhibitor
    Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections.
    Temafloxacin hydrochloride
  • HY-146328R
    PqsR/LasR-IN-2 (Standard)
    Inhibitor
    PqsR/LasR-IN-2 (Standard) is the analytical standard of PqsR/LasR-IN-2. This product is intended for research and analytical applications. PqsR/LasR-IN-2 (Compound 3) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-2 also inhibits hERG with the IC50 of 1.408 µM[1].
    PqsR/LasR-IN-2 (Standard)
  • HY-182295
    Negundoside
    Inhibitor
    Negundoside is an iridoid glycoside compound. Negundoside exhibits hepatoprotective effects, reduces ROS, lipid peroxidation and intracellular calcium ion levels, and prevents the decrease of mitochondrial membrane potential (MMP) and apoptosis (apoptosis). Negundoside has neuroprotective effects, improves behavioral deficits, alleviates oxidative damage, and ameliorates cerebral infarction. Negundoside also possesses antibacterial and antiparasitic activities.
    Negundoside
  • HY-139763
    Antibacterial agent 46
    Inhibitor
    Antibacterial agent 46 is an antibacterial agent extracted from patent WO2013030735A1, example 9. Antibacterial agent 46 can be used for the research of bacterial infections.
    Antibacterial agent 46
  • HY-132918
    Antibacterial agent 30
    Inhibitor
    Antibacterial agent 30 demonstrates excellent in vitro activity against Xoo with EC50 value of 1.9 μg/mL.
    Antibacterial agent 30
  • HY-144280
    MsbA-IN-2
    Inhibitor
    MsbA-IN-2 (compound 12) is a potent lipopolysaccharide transporter MsbA inhibitor with an IC50 of 2 nM for E. coli MsbA.
    MsbA-IN-2
  • HY-149379
    DNA gyrase B-IN-3
    Inhibitor
    DNA gyrase B-IN-3 (Compound A) is a bacterial DNA gyrase B inhibitor (IC50: < 10 nM). DNA gyrase B-IN-3 has antibacterial activity against gram-positive strains.
    DNA gyrase B-IN-3
  • HY-144727
    Anti-inflammatory agent 11
    Inhibitor
    Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research.
    Anti-inflammatory agent 11
  • HY-100528R
    Nanchangmycin (Standard)
    Inhibitor
    Nanchangmycin (Standard) is the analytical standard of Nanchangmycin. This product is intended for research and analytical applications. Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2].
    Nanchangmycin (Standard)
  • HY-P5625
    ROAD-1
    Inhibitor
    ROAD-1 is an oral mucosal α-defensin of Rhesus Macaque. ROAD-1 is active against S. aureus, E. coli, and C. albicans.
    ROAD-1
Cat. No. Product Name / Synonyms Application Reactivity