531-59-9
531-59-9
Chemical Structure
Herniarin
Synonym(s): Methylumbelliferone
- CAS No.: 531-59-9
- Formula:C10H8O3
- Molecular Weight:176.17
IUPAC Name: 7-methoxy-2H-chromen-2-one
InChIKey: LIIALPBMIOVAHH-UHFFFAOYSA-N
SMILES: O=C1C=CC2=CC=C(OC)C=C2O1
Biological Activity: Herniarin is a natural coumarin occurs in some flowering plants with anticancer effects. Herniarin results in a significant decrease in cell viability by inducing apoptosis in MCF-7 cells. Herniarin also has anti-dermatophytic activity. Herniarin can be used for the study of bladder cancer and breast cancer[1][2].
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Herniarin | 99.55% | Herniarin is a natural coumarin occurs in some flowering plants with anticancer effects. Herniarin results in a significant decrease in cell viability by inducing apoptosis in MCF-7 cells. Herniarin also has anti-dermatophytic activity. Herniarin can be used for the study of bladder cancer and breast cancer. | ||||||||||||||||||||
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Herniarin (Standard) | ≥98% | Herniarin (Standard) (Methylumbelliferone (Standard)) is the analytical standard of Herniarin (HY-N1366). This product is intended for research and analytical applications. Herniarin is a natural coumarin occurs in some flowering plants with anticancer effects. Herniarin results in a significant decrease in cell viability by inducing apoptosis in MCF-7 cells. Herniarin also has anti-dermatophytic activity. Herniarin can be used for the study of bladder cancer and breast cancer. | ||||||||||||||||||||
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Herniarin-d3 | 98.0% | Herniarin-d3 is the deuterium labeled Herniarin (HY-N1366). Herniarin is a natural coumarin occurs in some flowering plants with anticancer effects. Herniarin results in a significant decrease in cell viability by inducing apoptosis in MCF-7 cells. Herniarin also has anti-dermatophytic activity. Herniarin can be used for the study of bladder cancer and breast cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-133091R7-Ethoxycoumarin (Standard) -
Similarity Score 0.88
HY-W0676734-Methoxycoumarin -
Similarity Score 0.87
HY-N207447-Acetoxycoumarin -
Similarity Score 0.86
HY-N1406R6-Methylcoumarin (Standard) -
Similarity Score 0.86
HY-N5092R7-Methylcoumarin (Standard) -
Similarity Score 0.86
HY-N0573Umbelliferone -
Similarity Score 0.86
HY-W777393Umbelliferone-13C6 -
Similarity Score 0.86
HY-N66566-Hydroxycoumarin -
Similarity Score 0.85
HY-D01284-Methylherniarin -
Explore the MedChemAI to find more analogs
References
- [1]. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30. [Content Brief]
- [2]. Haghighitalab A, et al. Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug Chem Toxicol. 2014 Apr;37(2):156-62. [Content Brief]
