Chloride Channel
Cl− Channels
Chloride channels belong to a superfamily of ion channels that permit passive passage of anions, mainly chloride, across cell membrane. Chloride channels perform important roles in the regulation of cellular excitability, in transepithelial transport, cell volume regulation, and acidification of intracellular organelles. Chloride channels represent a group of potential drug targets.
The chloride channel protein (ClC) family comprises both chloride (Cl-) channels and chloride/proton (Cl-/H+) antiporters. In prokaryotes and eukaryotes, these proteins mediate the movement of Cl- ions across the membrane. In eukaryotes, ClC proteins play a role in the stabilization of membrane potential, epithelial ion transport, hippocampal neuroprotection, cardiac pacemaker activity and vesicular acidification.
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Chloride Channel Related Products (125)
Related Products (125)
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Antibodies (3)
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NPPB (Standard)
0 ImagesCat. No.: HY-101012RCAS No.: 107254-86-4NPPB (Standard) is the analytical standard of NPPB. This product is intended for research and analytical applications. NPPB is a blocker of the outwardly rectifying chloride channel (ORCC).
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Molluscicidal agent-2
0 ImagesCat. No.: HY-174441Molluscicidal agent-2 (Compound 16) is a molluscicide with an LC50 of 0.58 mg/mL against Monacha cartusiana snails. Molluscicidal agent-2 exerts its effect through a dual mode of action: gastrointestinal toxicity and GABAA-GluCl channel antagonism. Molluscicidal agent-2 can be used in research on agricultural pest control.
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Fenamic acid (Standard)
0 ImagesCat. No.: HY-W040265RCAS No.: 91-40-7Synonyms: N-Phenylanthranilic acid (Standard)Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent-.
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Tigolaner (Standard)
0 ImagesCat. No.: HY-109077RCAS No.: 1621436-41-6Synonyms: BAY-1272858 (Standard)
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Meticrane (Standard)
0 ImagesMeticrane (Standard) is the analytical standard of Meticrane. This product is intended for research and analytical applications. Meticrane is a diuretic. Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.
