1. Membrane Transporter/Ion Channel Neuronal Signaling Anti-infection
  2. GABA Receptor Parasite
  3. Tigolaner

Tigolaner  (Synonyms: BAY-1272858)

Cat. No.: HY-109077 Purity: 98.53%
COA Handling Instructions

Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent.

For research use only. We do not sell to patients.

Tigolaner Chemical Structure

Tigolaner Chemical Structure

CAS No. : 1621436-41-6

Size Price Stock Quantity
1 mg USD 200 In-stock
5 mg USD 449 In-stock
10 mg USD 718 In-stock
25 mg USD 1437 In-stock
50 mg USD 2300 In-stock
100 mg USD 3690 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent[1].

Molecular Weight

552.81

Formula

C21H13ClF8N6O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(C(C(C(F)(F)C(F)(F)F)=N1)=C(N2C=C(C(C=C3)=CC(C(NC4(CC4)C#N)=O)=C3Cl)C=N2)N1C)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (45.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8089 mL 9.0447 mL 18.0894 mL
5 mM 0.3618 mL 1.8089 mL 3.6179 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8089 mL 9.0447 mL 18.0894 mL 45.2235 mL
5 mM 0.3618 mL 1.8089 mL 3.6179 mL 9.0447 mL
10 mM 0.1809 mL 0.9045 mL 1.8089 mL 4.5223 mL
15 mM 0.1206 mL 0.6030 mL 1.2060 mL 3.0149 mL
20 mM 0.0904 mL 0.4522 mL 0.9045 mL 2.2612 mL
25 mM 0.0724 mL 0.3618 mL 0.7236 mL 1.8089 mL
30 mM 0.0603 mL 0.3015 mL 0.6030 mL 1.5074 mL
40 mM 0.0452 mL 0.2261 mL 0.4522 mL 1.1306 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tigolaner
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