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GHSR Related Products (67)
Related Products (67)
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Anamorelin
0 ImagesSynonyms: RC-1291; ONO-7643Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia.
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Anamorelin hydrochloride
0 ImagesSynonyms: RC-1291 hydrochloride; ONO-7643 hydrochlorideAnamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia.
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PF-5190457
0 ImagesSynonyms: PF-05190457PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36.
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JMV 2959
0 ImagesJMV 2959 is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32 nM.
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(S)-PF-5190457
0 ImagesCat. No.: HY-12584APurity: 99.27%Synonyms: (S)-PF-05190457(S)-PF-5190457 ((S)-PF-05190457) is the S-enantiomer of PF-5190457 (HY-12584). PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36.
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KARI 101
0 ImagesCat. No.: HY-186165CAS No.: 3061559-97-2KARI 101 is a blood-brain barrier permeable acid sphingomyelinase (ASM) inhibitor. KARI 101 directly inhibits ASM activity and reduces ceramide production. KARI 101 induces Ca2+ mobilization, activates AMPK and triggers GHSR1α internalization. KARI 101 can be used for the research of Alzheimer's disease.
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Relamorelin TFA
0 ImagesSynonyms: RM-131 TFA; BIM-28131 TFARelamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research.
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Macimorelin acetate
0 ImagesSynonyms: EP-1572 acetate; AEZS-130 acetate
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des-Gln14-Ghrelin
0 Imagesdes-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM.
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AZP-531
0 ImagesAZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.
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Meranzin hydrate
0 ImagesMeranzin hydrate is an orally active antidepressant and GHSR modulator. Meranzin hydrate significantly upregulates the expression levels of brain-derived neurotrophic factor and p-mTOR in the hippocampus via the ghrelin-growth hormone secretagogue receptor pathway. Meranzin hydrate regulates blood oxygen level-dependent signals in the hippocampus-thalamus-basal ganglia circuit, attenuates reward system activation, and promotes the normalization of related hormone levels. Meranzin hydrate effectively ameliorates depression-like behaviors and gastrointestinal hypomotility, and can be used in research related to depression and major depressive disorder.
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KARI 201 hydrochloride
0 ImagesKARI 201 hydrochloride is a selective, brain penetrant pand competitive acid sphingomyelinase (ASM) inhibitor with an IC50 of 338.3?nM. KARI 201 hydrochloride is a ghrelin receptor agonist. KARI 201 hydrochloride improves neuropathological features of Alzheimer's disease.
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JMV 2959 hydrochloride
0 ImagesCat. No.: HY-U00433ACAS No.: 2448414-54-6JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
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GRF (1-29) amide (rat)
0 ImagesSynonyms: rGHRH(1-29)NH2GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.
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Obestatin(human)
0 ImagesObestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.
