HBV
Hepatitis B virus
HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.
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HBV Related Products (384)
Related Products (384)
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Antibodies (2)
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Punicalin (Standard)
0 ImagesCat. No.: HY-N0639RCAS No.: 65995-64-4Punicalin (Standard) is the analytical standard of Punicalin. This product is intended for research and analytical applications. Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity.
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HBV-IN-10
0 ImagesCat. No.: HY-145053CAS No.: 2716907-16-1HBV-IN-10 is an enantiomer of compound 6 (WO2021204258A1). Compound 6 is a hepatitis B surface antigen (HBsAg) inhibitor (0.001 μM< EC50 ≤0.05 μM). From patent WO2021204258A1, compound 6.
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Telbivudine (Standard)
0 ImagesSynonyms: Epavudine (Standard); L-Thymidine (Standard); NV 02B (Standard)
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Inarigivir ammonium (Standard)
0 ImagesCat. No.: HY-101954ARCAS No.: 2172788-92-8Synonyms: ORI-9020 ammonium (Standard); SB-9000 ammonium (Standard)Inarigivir ammonium (Standard) is the analytical standard of Inarigivir ammonium (HY-101954A). This product is intended for research and analytical applications. Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) ammonium acts as a RIG-I (Retinoic acid-inducible gene-I) agonist to activate cellular innate immune responses.
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Morphothiadin mesylate
0 ImagesCat. No.: HY-108917ACAS No.: 1646361-04-7Synonyms: GLS4 mesylate
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Vesatolimod (Standard)
0 ImagesCat. No.: HY-15601RCAS No.: 1228585-88-3Synonyms: GS-9620 (Standard)Vesatolimod (Standard) is the analytical standard of Vesatolimod. This product is intended for research and analytical applications. Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM.
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HBV-IN-56
0 ImagesCat. No.: HY-181348CAS No.: 2564693-71-4HBV-IN-56 is an orally active HBsAg production inhibitor. HBV-IN-56 inhibits HBsAg production both in vitro and in vivo. HBV-IN-56 can be used for the research of chronic hepatitis B virus infection.
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NPD8716
0 ImagesCat. No.: HY-115668CAS No.: 956944-02-8NPD8716 is a sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with a human IC50 of 17.8 μM. NPD8716 interacts with NTCP, blocks the binding of HBV preS1 to NTCP, impairs NTCP-mediated bile acid uptake, inhibits NTCP transporter activity, and blocks the attachment of viruses to host hepatocytes. NPD8716 inhibits the entry of HBV and HDV into host cells. NPD8716 can be used in studies related to hepatitis B virus infection and hepatitis D virus infection.
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Lagociclovir
0 ImagesCat. No.: HY-14844CAS No.: 92562-88-4Synonyms: MIV-210
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OSS_128167 (Standard)
0 ImagesCat. No.: HY-107454RCAS No.: 887686-02-4OSS_128167 (Standard) is the analytical standard of OSS_128167 (HY-107454). This product is intended for research and analytical applications. OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects.
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Bay 41-4109 racemate (Standard)
0 ImagesCat. No.: HY-100029ARCAS No.: 298708-79-9Bay 41-4109 (racemate) (Standard) is the analytical standard of Bay 41-4109 (racemate). This product is intended for research and analytical applications. BAY 41-4109 racemate is the racemate of BAY 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
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Nicotinamide-d3
0 ImagesCat. No.: HY-B0150S3CAS No.: 2162970-00-3Synonyms: Niacinamide-d3; Nicotinic acid amide-d3Nicotinamide-d3 (Niacinamide-d3) is deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.
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Vonafexor (Standard)
0 ImagesCat. No.: HY-109197RCAS No.: 1192171-69-9Synonyms: EYP001 (Standard)Vonafexor (Standard) is the analytical standard of Vonafexor (HY-109197). This product is intended for research and analytical applications. Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFNα. Vonafexor can be used for anti-HBV research.
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Coclauril
0 ImagesCat. No.: HY-N3609CAS No.: 127350-68-9
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Famciclovir-d6
0 ImagesCat. No.: HY-17426S1CAS No.: 2587293-47-6Synonyms: BRL 42810-d6
